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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Prevalence of transfusion transmitted virus (TTV) genotypes among HCC patients in Qaluobia governorate | Virology Journal BioMed Central Research Prevalence of transfusion transmitted virus TTV genotypes among HCC patients in Qaluobia governorate Mohamed M Hafez 1 Sabry M Shaarawy1 Amr A Hassan2 Rabab F Salim2 Fatma M Abd El Salam2 and Amal E Ali2 Open Access Address 1Virology and Immunology Unit Cancer Biology Department National Cancer Institute Cairo University 1st Kasr El-Aini st Cairo Egypt and 2Biochemistry department Benha Faculty of medicine Benha University Banha Egypt Email Mohamed M Hafez - Mohhafez@nci.edu.eg Sabry M Shaarawy - shaarawysabry@yahoo.com Amr A Hassan - Amrhassan@hotmail.com Rabab F Salim - modernpharmacy1@yahoo.com Fatma M Abd El Salam - fatma@yahoo.com Amal E Ali - amalidris348@hotmail.com Corresponding author Published 6 December 2007 Received 27 July 2007 Accepted 6 December 2007 Virology Journal 2007 4 135 doi 10.1186 1743-422X-4-135 This article is available from http www.virologyj.cOm content 4 1 135 2007 Hafez et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background Transfusion Transmitted virus TTV is a novel single-stranded DNA virus that was identified in patients with post-transfusion hepatitis of non-A-G type. Clinical significance of TTV infection was analyzed in Egyptian hepatocellular carcinoma HCC patients. The present study attempted to clarify these issues in Egypt particularly in Qaluobia governorate a country known for its high endemicity of liver disease and hepatotropic viruses. Methods TTV are determined in the serum of 60 samples obtained from HCC and liver cirrhosis LC patients and 30 healthy individuals. TTV DNA is amplified by nested-PCR with TTV-specific mixed primers