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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Video assisted thoracoscopic resection of a posterior mediastinal Castleman’s tumor. | Shetty et al. Journal of Cardiothoracic Surgery 2011 6 113 http www.cardiothoracicsurgery.Org content 6 1 113 JCTS JOURNAL OF CARDIOTHORACIC SURGERY CASE REPORT Open Access Video assisted thoracoscopic resection of a posterior mediastinal Castleman s tumor Shohan Shetty Robert A Brenes Lucian Panait and Juan A Sanchez Abstract Castleman s disease CD or angiofollicular lymph node hyperplasia is a rare spectrum of lymphoproliferative disorders. CD tumors are commonly localized in the mediastinum and are usually asymptomatic. The mainstay of treatment is surgical resection and has typically been performed using open thoracotomy. Few reports in the literature describe video assisted thoracoscopic resection of these tumors. The differential diagnosis for mediastinal masses is extensive and CD tumors although uncommon should be considered. We describe a case report of a posterior mediastinal Castleman s tumor adherent to the esophagus which was resected thoracoscopically and review the literature. Introduction First described in 1954 Castleman s disease CD 1 is a rare lymphoproliferative disorder involving lymphocyte proliferation and excessive cytokine production. The characteristic lymphoid tumors may occur singly or in a multicentric pattern the latter being more commonly associated with signs and symptoms including fever weight loss anemia anorexia and low white blood cell count. Surgical resection is the mainstay of treatment for unicentric mediastinal CD 2 and has been typically performed via standard thoracotomy 3-5 . While videoassisted thoracoscopic surgical VATS resection has become an effective and reliable option for excising mediastinal masses 6 7 very few reports describe resection of mediastinal CD using this approach 8-11 . Because these tumors are highly vascular and often have dense adhesions to the surrounding tissue they must be approached with great care especially in the mediastinum given the close proximity to vital structures 4 12 . We report our