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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Using quantitative breath sound measurements to predict lung function following resection. | Morice et al. Journal of Cardiothoracic Surgery 2010 5 81 http www.cardiothoracicsurgery.Org content 5 1 81 JOTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Using quantitative breath sound measurements to predict lung function following resection 1 1 f A I- 1 2 1 1 Rodolfo C Morice Carlos A Jimenez Georgie A Eapen Reza J Mehran Leendert Keus David Ost Abstract Background Predicting postoperative lung function is important for estimating the risk of complications and long-term disability after pulmonary resection. We investigated the capability of vibration response imaging VRI as an alternative to lung scintigraphy for prediction of postoperative lung function in patients with intrathoracic malignancies. Methods Eighty-five patients with intrathoracic malignancies considered candidates for lung resection were prospectively studied. The projected postoperative ppo lung function was calculated using perfusion scintigraphy ventilation scintigraphy and VRI. Two sets of assessments made one for lobectomy and one for pneumonectomy. Clinical concordance was defined as both methods agreeing that either a patient was or was not a surgical candidate based on a ppoFEV1 and ppoDLCO 40 . Results Limits of agreement between scintigraphy and VRI for ppo following lobectomy were -16.47 to 15.08 mean difference -0.70 95 CI -2.51 to 1.12 and for pneumonectomy were -23.79 to 19.04 mean difference -2.38 95 CI -4.69 to -0.07 . Clinical concordance between VRI and scintigraphy was 73 for pneumonectomy and 98 for lobectomy. For patients who had surgery and postoperative lung function testing n 31 ppoFEV1 using scintigraphic methods correlated with measured postoperative values better than projections using VRI adjusted R2 0.32 scintigraphy 0.20 VRI however the difference between methods failed to reach statistical significance. Limits of agreement between measured FEV1 postoperatively and ppoFEV1 based on perfusion scintigraphy were -16.86 to 23.73 mean difference 3.44
