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Thông thường thấy trong các khối u ác tính huyết học; postchemotherapy với giảm bạch cầu trung tính kéo dài 2) Có thể hiện như sốt giảm bạch cầu trung mà không có dấu hiệu hoặc triệu chứng đầu mối và khôngantibacterials; siêu âm và chụp cắt lớp vi tính | Infectious Syndromes 262 1 Affects 75 of childbearing women 2 40 of affected women have a 2nd episode 5 have recurrent disease 4 episodes per year Cutaneous syndromes 1 Intertriginous infection In warm moist areas in diabetic and obese patients 2 Folliculitis 3 Balanitis May involve scrotum 4 Paronychial infection Swelling tenderness erythema around nail 5 Disseminated Macronodular lesions lesions resembling ecthyma gangrenosum Urinary candidiasis Colony count not predictive of disease clinical judgment required Disseminated disease acute or subacute 1 Ocular candidiasis Up to 30 of patients with fungemia may develop endophthalmitis 2 Candidemia Only 25 of patients with extensive organ disease have positive blood cultures 3 Meningitis Especially in patients with intravenous drug abuse postneurosurgery and central nervous system CNS shunt infections 4 Osteomyelitis Usually from hematogenous dissemination 5 Peritonitis From peritoneal dialysis bowel surgery or perforated bowel 6 Endocarditis Most common form of fungal infective endocarditis large vegetations Hepatosplenic candidiasis Chronic disseminated candidiasis 1 Typically seen in hematologic malignancies postchemotherapy with prolonged neutropenia 2 May present as neutropenic fever without focal signs or symptoms and fail to respond to antibacterials ultrasound and computed tomography CT may be normal initially during the period of neutropenia 3 During neutropenic recovery fever continues with elevation of liver enzymes especially alkaline phosphatase abdominal ultrasound CT or magnetic resonance imaging commonly shows multiple small round hypoechoic or low-attenuated lesions scattered throughout the liver and spleen lesions can later calcify 4 Predominantly a clinical and radiographic diagnosis as liver biopsy is commonly false-negative blood cultures are usually negative Treatment Depends on Syndrome and Type of Candida sp Oral thrush Oral nystatin clotrimazole troches oral fluconazole Esophagitis Oral .
