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This research showed how animal models can predict patient response not just to a particular medicine, but to different combinations of therapy – a critical factor in cancer treatment. for example, animal studies with combinations of tamoxifen and aromatase inhibitors did not show any improvement over established treatments. Professor brodie described how aromatase inhibitor therapy alone had been shown to be the most effective16. Her preliminary research excited doctors who ran the first clinical trial. It was a success and aromatase inhibitors were approved for use in patients with oestrogen- fuelled breast cancer. Later studies with patients showed that sequential treatment. | FM 4-02.17 PREVENTIVE MEDICINE SERVICES HEADQUARTERS DEPARTMENT OF THE ARMY DISTRIBUTION RESTRICTION Approved for public release distribution is unlimited. FM 4-02.17 FIELD MANUAL NO. 4-02.17 HEADQUARTERS DEPARTMENT OF THE ARMY Washington DC 28 August 2000 PREVENTIVE MEDICINE SERVICES TABLE OF CONTENTS PREFACE Page v CHAPTER 1. MEDICAL THREAT. 1-1 1-1. General . 1-1 1-2. Historical Perspective. 1-2 1-3. Disease and Nonbattle Injury. 1-3 1-4. Individual and Unit Preventive Medicine Measures . 1-6 1- 5. Preventive Medicine Employment in Defeating the Threat. 1-6 CHAPTER 2. ROLE OF THE SOLDIER AND UNIT LEADER. 2-1 2- 1. General . 2-1 2-2. Role of the Individual Soldier. 2-1 2-3. Role of Unit Leaders . 2-4 CHAPTER 3. PREVENTIVE MEDICINE STAFF IN A THEATER OF OPERATIONS. 3-1. Staffing . 3-2. Army Service Component Command . 3-3. Medical Command. 3-4. Corps. 3-5. Medical Brigade. 3-6. Medical Group . 3-7. Division. 3-8. Separate Brigade. 3-9. Armored Cavalry Regiment. 3-10. Special Operations Forces. 3-11. Area Support Medical Battalion. 3-12. Engineer Units. 3-13. Military Police Units . 3-14. Civil Affairs Units. 3-15. Quartermaster Units. 3 1 3 1 3 -1 3- 1 3- 1 3 -2 3 2 3 2 3- 3 3 -3 3 -3 3 -4 3- 4 3 -4 3 -5 3 -5 DISTRIBUTION RESTRICTION Approved for public release distribution is unlimited. i FM 4-02.17 Page CHAPTER 4. Section I. 4-1. 4-2. 4-3. 4-4. 4-5. 4-6. Section 4-7. 4-8. 4-9. 4-10. 4-11. II. 4-12. 4-13. 4-14. 4-15. 4-16. 4-17. 4-18. 4-19. PREVENTIVE MEDICINE DETACHMENTS AND ACTIVITIES . Table of Organization and Equipment Detachments. General . Operational Principles. Operational Concept for the Preventive Medicine Detachment Sanitation . Location of the Preventive Medicine Detachment Sanitation . Function of the Preventive Medicine Detachment Sanitation . Operational Concept for the Preventive Medicine Detachment Entomology . Location of the Preventive Medicine Detachment Entomology . Function of the Preventive Medicine Detachment Entomology . Basis of .