Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Chủ đề Liều dùng cho nhãn điều trị mụn rộp rộp môi Kết quả herpes sinh dục chế độ dùng thuốc là không đủ để điều trị rộp môi herpes. Sử dụng liều cao hơn có thể là cần thiết để giảm thời gian chữa lành tổn thương | General Non-antiretroviral Antiviral Drugs 163 Table 3.8 Clinical Studies and Published Reports that Support the Use of Famciclovir Topic Findings Reference Dosage for off-label treatment for herpes labialis Genital herpes regimen dosing is not sufficient for treatment of herpes labialis. Use of higher doses may be necessary to reduce lesion healing time e.g. 500 mg TID for 5 days . 157 Efficacy in reducing number of recurrences of genital herpes Famciclovir delays the time of the first recurrence of genital herpes. The number of patients remaining lesion free was 3 times higher in famciclovir than in placebo recipients. 158 159 Comparison of famciclovir with acyclovir for treatment of HSV in HIV-positive patients Both acyclovir and famciclovir are well tolerated generally safe to use and effective 160 Symptomatic and asymptomatic viral shedding in women For those women with a history of recurrent genital herpes famciclovir reduces the frequency and delays the onset of viral shedding. 161 Genital herpes recurrences Famciclovir is effective in increasing the time to first recurrence of genital herpes and increasing the number of recurrence-free patients. 159 160 Suppression of HSV reactivation in HIVpositive patients Famciclovir treatment of 500 mg twice daily for 8 weeks significantly reduces symptoms and viral shedding. 161 Herpes zoster in immunocompetent patients reduction of postherpetic neuralgia Famciclovir is effective at reducing PHN when used 500 mg t.i.d. for 7 days especially among persons 50 years of age and older. 162 163 continued 164 Antiviral Agents Table 3.8 Continued Topic Findings Reference Rapid resolution of zoster-associated pain Famciclovir is as effective and more convenient than acyclovir for rapid resolution of zoster-associated pain. 163 164 Ophthalmic zoster Famciclovir 500 mg 3 times daily was well tolerated and demonstrated efficacy similar to acyclovir 800 mg 5 times daily 153 Ramsey Hunt syndrome A 7-10 day course of famciclovir 500
