Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The inheritance of halothane susceptibil | Génét. Sél. Evol. 1983 15 l 65-82 The inheritance of halothane susceptibility in pigs A.E. CARDEN W.G. HILL and A.J. WEBB A.R.C. Animal Breeding Research Organisation West Mains Road Edinburgh EH9 3JQ U.K. On leave from E.E.R.A. Pergamino I.N.T.A. c.c. 31 2700 Pergamino Buenos Aires Argentina Institute of Animal Genetics University of Edinburgh West Mains Road Edinburgh EH9 3JN U.K. Summary The mode of inheritance of the reaction to halothane anaesthesia in pigs was investigated in 40 litters by 14 sires in a Pietrain-Hampshire synthetic population and in 60 litters by 28 sires in a British Landrace experimental herd. The single-recessive mode of inheritance was tested as a hypothesis in the context of I a single-locus-two-alleles model where both the heterozygotes and one of the homozygotes react to the anaesthetic and II a two-locus model involving a susceptibility locus and a suppressor locus both assumed to have two alleles. Maximum likelihood techniques were used to fit the models to the data. The results of the single-locus analysis did not disprove the single-recessive hypothesis in Pietrain-Hampshire. The same analysis provided strong evidence to reject a strictly recessive mode of inheritance in British Landrace the parameter estimates indicated that about a quarter of the heterozgotes were positive reactors after the halothane test. Although not conclusive the two-locus analysis in Pietrain-Hampshire indicated that the addition of a suppressor locus to a single-recessive model could improve the genetic explanation of halothane testing results. The two-locus analysis also rejected the single-recessive hypothesis as the mode of inheritance of halothane susceptibility in British Landrace pigs. Key-words Halothane susceptibility inheritance pigs. Resume ưhérédité de la sensibilité à I halothane chez le pore Le mode de transmission de la reaction à 1 anesthésie à 1 halothane a été examine dans 40 portệes issues de 14 verrats dans une population sỵnthétique .
