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If you think sticking your head in the text books will give you all the answers about workplace cancer risks, you’d be wrong. Barely one in every 100 chemicals used at work has been systematically tested. Finding out if there is a workplace risk requires union vigilance. That means doing your own detective work. Unions have been instrumental in first identifying a number of workplace cancers, from bladder cancer in dye workers to liver cancer in vinyl chloride workers. Remember, keep it as simple as possible. A quick discussion at a union meeting might provide all the information you need | Chapter 8 Cancer of the Larynx Jay F. Piccirillo and Irene Costas INTRODUCTION The larynx positioned in the neck slightly below the point where the pharynx divides into separate respiratory and digestive tracts is critical to breathing swallowing and speaking. The glottis is the portion of the larynx where the vocal cords are located. The area above the vocal cords is referred to as the supraglottis and that below the vocal cords as the subglottis. This chapter provides survival analyses for 14 950 histologically confirmed adult cases of cancer of the larynx. Cases were obtained from the Surveillance Epidemiology and End Results SEER Program of the National Cancer Institute NCI . Cancer of the larynx is second only to oral cavity cancer as the most common cancer of the upper aerodigestive tract 1 . Tobacco and alcohol use are widely recognized as the key causative factors for many of these tumors 2 . The cell type of origin for the vast majority of these tumors is squamous cell 3 . MATERIAL AND METHODS The NCI contracts with medically oriented nonprofit institutions such as universities and state health departments to obtain data on all cancers diagnosed in residents of the SEER geographic areas. SEER collects data on all invasive and in situ cancers except basal cell and squamous cell carcinomas of the skin and in situ carcinoma of the uterine cervix. SEER selects participating institutions on the basis of two criteria their ability to operate and maintain a populationbased cancer reporting system and the epidemiologic significance of their population subgroups. At times registries will withdraw at times registries will be added. This analysis is based on data from 12 geographic areas that collectively contain about 14 of the total US population. The areas are the States of Connecticut Iowa New Mexico Utah and Hawaii the metropolitan areas of Detroit Atlanta San Francisco Seattle San Jose and Los Angeles and 10 counties in rural Georgia. Los Angeles contributed .