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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Construction of a high-resolution genetic linkage map and comparative genome analysis for the reef-building coral Acropora millepora. | Open Access Construction of a high-resolution genetic linkage map and comparative genome analysis for the reef-building coral Acropora millepora Shi Wang Lingling Zhang Eli Meyer and Mikhail V Matz Address Section of Integrative Biology School of Biological Sciences University of Texas at Austin 1 University Station C0930 Austin TX 78712 USA. Correspondence Shi Wang. Email swang@mail.utexas.edu Published 10 November 2009 Genome Biology 2009 10 R126 doi 10.1186 gb-2009-l0-ll-rl 26 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2009 10 11 R126 Received 30 July 2009 Revised l2 October 2009 Accepted 10 November 2009 2009 Wang et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Worldwide coral reefs are in decline due to a range of anthropogenic disturbances and are now also under threat from global climate change. Virtually nothing is currently known about the genetic factors that might determine whether corals adapt to the changing climate or continue to decline. Quantitative genetics studies aiming to identify the adaptively important genomic loci will require a high-resolution genetic linkage map. The phylogenetic position of corals also suggests important applications for a coral genetic map in studies of ancestral metazoan genome architecture. Results We constructed a high-resolution genetic linkage map for the reef-building coral Acropora millepora the first genetic map reported for any coral or any non-Bilaterian animal. More than 500 single nucleotide polymorphism SNP markers were developed most of which are transferable in populations from Orpheus Island and Great Keppel Island. The map contains 429 markers 393 gene-based SNPs and 36 .
