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Tiến bộ trong nền kinh tế toàn cầu hiện nay chủ yếu dựa trên công nghệ cải tiến và phân phối của mình để hoạt động rộng lớn của con người. Thị trường toàn cầu và sản xuất, với phong trào và vận chuyển dễ dàng của nó, một lực lượng lao động ít tốn kém, và các quy định nghiêm ngặt ít, đã được tìm thấy được các hoạt động liên quan chặt chẽ. Với những loại tình huống, con người tiếp xúc với các chất hóa học độc hại trở nên rõ ràng hơn. Không được kiểm soát,. | 8 Chemical Substances and Carcinogenicity 8.1 INTRODUCTION Progress in a global economy is now primarily based on improved technology and its distribution to extensive human activities. The global market and production with its easy movement and transportation a less expensive workforce and less stringent regulations have been found to be closely interrelated activities. With these kinds of situations human exposure to hazardous chemical substances becomes more evident. Uncontrolled irrational transboundary movement of hazardous chemical substances and waste disposal have caused health hazards in communities. Occupational and environmental exposure to many chemical substances industrial solvents metals plastics and asbestos such as in mining shipwrecks and production and use of pesticides in agriculture and horticulture and many others is known to have effects on health. To contain any kind of untoward incident at the workplace or in the community proper management of hazardous chemical substances is a must. To achieve this workers managers regulatory agencies and the public at large require ready information about the good and bad aspects of chemical substances so that they have proper knowledge. The following pages provide in brief lists of known carcinogens suspected carcinogens and probable carcinogens. Proper use and careful management of chemical substances protect human health and safety and the living environment. 8.2 CARCINOGENS AND CARCINOGENESIS Workers come in contact with a large number of chemical substances in work areas as does the general public. The commonly found chemical carcinogens are grouped under 1 polycyclic aromatic hydrocarbons PAHs 2 nitroso compounds 3 halogenated hydrocarbons solvents e.g. carbon tetrachloride chloroform trichloroethylene and methylene chloride 4 inorganic metals and minerals beryllium cadmium nickel cobalt chromium asbestos and arsenic and 5 naturally occurring chemical substances aflatoxins . Halogenated .