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The first edition of Toxicological Chemistry (1989) was written to bridge the gap between toxicology and chemistry. It defined toxicological chemistry as the science that deals with the chemical nature and reactions of toxic substances, their origins and uses, and the chemical aspects of their exposure, transformation, and elimination by biological systems. It emphasized the chemical formulas, structures, and reactions of toxic substances. The second edition of Toxicological Chemistry (1992) was significantly enlarged and increased in scope compared to the first edition. In addition to toxicological chemistry, it addressed the topic of environmental biochemistry, which pertains to the effects of environmental chemical substances on living systems and the influence of life-forms. | toxicological Chemistryand biochemistry THIRD EDITION Copyright 2003 by CRC Press LLC TOXICOLOGICAL CHEMISTRYand biochemistry THIRD EDITION Stanley E. Manahan . LEWIS PUBLISHERS A CRC Press Company Boca Raton London New York Washington D.C. Copyright 2003 by CRC Press LLC Library of Congress Cataloging-in-Publication Data Manahan Stanley E. Toxicological chemistry and biochemistry by Stanley E. Manahan.-- 3rd ed. p. cm. Includes bibliographical references and index. ISBN 1-56670-618-1 1. Toxicological chemistry. 2. Environmental chemistry. 3. Biochemical toxicology. I. Title. RA1219.3 .M36 2002 815.9 001 54--dc21 2002072486 This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use. Neither this book nor any part may be reproduced or transmitted in any form or by any means electronic or mechanical including photocopying microfilming and recording or by any information storage or retrieval system without prior permission in writing from the publisher. The consent of CRC Press LLC does not extend to copying for general distribution for promotion for creating new works or for resale. Specific permission must be obtained in writing from CRC Press LLC for such copying. Direct all inquiries to CRC Press LLC 2000 N.W. Corporate Blvd. Boca Raton Florida 33431. Trademark Notice Product or corporate names may be trademarks or registered trademarks and are used only for identification and explanation without intent to infringe. Visit the CRC Press Web site at www.crcpress.com 2003 by CRC Press LLC Lewis Publishers is an imprint of CRC Press LLC No claim to original U.S. Government works International Standard Book Number 1-56670-618-1 .