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Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Prevalence and Clinical Characterization of Gastric Helicobacter Species Infection of Dogs and Cats in Korea | J. Vet. Sci. 2002 3 2 123-133 JOURNAL OF Veterinary Science Prevalence and Clinical Characterization of Gastric Helicobacter Species Infection of Dogs and Cats in Korea Cheol-Yong Hwang Hong-Ryul Han and Hwa-Young Youn Department of Veterinary Internal Medicine College of Veterinary Medicine Seoul National University Seoul 151-742 Korea Received Dec. 16 2001 Accepted May 16 2002 ABSTRACT This study was carried out to evaluate the prevalence and clinical characterizations of gastric Helicobacter spp. infection of dogs and cats in Korea. The prevalence of Helicobacter spp. infection of dogs and cats determined by urease test was 78.4 and 64 respectively although Helicobacter genus-specific PCR assay showed that it was 82.3 and 84 . Urease m apping re sults based on urease test show ed that total positive rate of tested tissues from clinically abnorm al dogs w as significantly higher than that from clinically normal dogs p 0.0018 Odds ratio 6.118 95 Confidence Interval 1.96 19.103 . These findings were consistent with the re sults of Helicobacter genus-specific PCR assay which showed that positive rate of the fundus 100 and the antrum 100 of clinically abnorm al dogs w as significantly higher than that of same gastric regions of clinically norm al dogs 77.5 and 67.5 respectively . In comparison of gastric regions betw een clinically norm al dogs and abnorm al dogs positive rate of ure ase test for the fundus 100 and body 90.9 in clinically abnorm al dogs w as significantly higher than that of abnorm al dogs 72.5 and 57.5 respectively p 0.05 . The results of urease m apping in dogs and cats also indicated that Helicobacter coloniz ation in the fundus was more dense com p ared with the density in the body and antrum. In Helicobacter species-specific P CR assay for dogs 32 of 42 fundic tissues 76.2 were positive for H. heilmannii and two 4.8 were positive for H. felis. In cats 18 of 21 fundic tissues 85.7 w ere p ositive for H. heilmannii and 2 9.5 were positive for H. .
