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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Annotations for all by all - the BioSapiens network. | Correspondence Annotations for all by all - the BioSapiens network Janet Thornton for the BioSapiens Network Address European Bioinformatics Institute Hinxton CB10 1SD UK. Email thornton@ebi.ac.uk. Published 10 February 2009 Genome Biology 2009 10 401 doi 10.1186 gb-2009-10-2-401 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2009 10 2M01 2009 BioMed Central Ltd Abstract The BioSapiens network has developed a distributed infrastructure for genome and proteome annotation by laboratories anywhere in the world. Over the last five years the BioSapiens network has developed a distributed infrastructure to facilitate the combined annotation of genomes and proteomes by laboratories scattered throughout Europe. In a series of four review articles published in Genome Biology 1-4 members of the consortium have collaborated to provide an overview of current methods and challenges for the future. In total there are now thousands of completed genomes in the public domain and with the second revolution in DNA sequencing technology many many more will be determined. However DNA sequence is merely a string of letters it must be interpreted in terms of the RNA and proteins that it encodes and the promoter and regulatory regions that control transcription and translation. Annotation can be described as the process of defining the biological role of a molecule in all its complexity and mapping this knowledge onto the relevant gene products encoded by genomes Figure 1 . The main objective of BioSapiens a Network of Excellence funded by the European Commission is to provide an infrastructure and tools to support a large-scale concerted effort to annotate genome and proteome data by laboratories distributed around Europe. The Network brought together 26 laboratories in Europe to create a Virtual Institute for Genome Annotation divided into nodes each focused on one aspect of genome annotation. The network provides a focus for
