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The benefit-to-risk ratio of blood products needs constant evaluation. Blood products, as therapeutic agents, have had the test of time but lack the evidence we expect from other medicinals. Blood, an organ, is used as a pharmaceutical agent by the medical profession, due to the achievements in collection, processing, banking, and distribution. The fact that the most common risk of blood transfusion isblood delivery error supports the notion that blood is handled as a pharmaceutical agent. | Basics of Blood Management Petra Seeder and A eh Shander Basics of Blood Management Basics of Blood Management Petra Seeber MD Department of Anesthesiology Critical Care Medicine Pain Management Emergency Medicine HELIOS Klinik Blankenhain Wirthstr. 5 99444 Blankenhain Germany Aryeh Shander MD FCCM FCCP Chief Department of Anesthesiology Critical Care Medicine Pain Management and Hyperbaric Medicine Englewood Hospital and Medical Center 350 Engle Street Englewood NJ 07631 and Clinical Professor of Anesthesiology Medicine and Surgery Mount Sinai School of Medicine Mount Sinai Hospital New York hirst edition Blackwell .