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A second paragraph will address Diffuse Reflectance Spectroscopy (DRS) that has been tested on phantoms mimicking melanoma. A third paragraph will talk about two techniques that have given preliminary results on potential Breslow index determination: the first one, infrared microimaging, performed on fixed and paraffin-embedded tissues (i.e. after excision of the tumour) and the second one, photoacoustic microscopy, performed in vivo on mice on which melanoma human cells were xenografted. Finally a fourth paragraph will address the topic of two techniques that have already shown excellent results in the area of skin thickness determination but for which no studied has yet been carried out to determine Breslow thickness although. | HIV AND AIDS -UPDATES ON BIOLOGY IMMUNOLOGY EPIDEMIOLOGY AnD TREATMENT STRATEGIES Edited by Nancy Dumais INTECHWEB.ORG HIV and AIDS - Updates on Biology Immunology Epidemiology and Treatment Strategies Edited by Nancy Dumais Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Alenka Urbancic Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat Image Copyright jocic 2010. Used under license from Shutterstock.com First published October 2011 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org HIV and AIDS - Updates on Biology Immunology Epidemiology and Treatment Strategies Edited by Nancy Dumais p. cm. 978-953-307- 665 -2 ikrrr .