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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Genomic neighborhoods for Arabidopsis retrotransposons: a role for targeted integration in the distribution of the Metaviridae. | Research Open Access Genomic neighborhoods for Arabidopsis retrotransposons a role for targeted integration in the distribution of the Metaviridae Brooke D Peterson-Burch Dan Nettleton and Daniel F Voytas Addresses National Animal Disease Center 2300 N Dayton Ave Ames IA 50010 USA. Department of Statistics 124 Snedecor Hall Iowa State University Ames IA 50011 USA. Department of Genetics Development and Cell Biology 1035A Roy J. Carver Co-Lab Iowa State University Ames IA 50011 USA. Correspondence Daniel FVoytas. E-mail voytas@iastate.edu Published 29 September 2004 Received 3 June 2004 Genome Biology 2004 5 R78 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2004 5 10 R78 Revised 3 August 2004 Accepted 2 September 2004 2004 Peterson-Burch et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. issno 1465-6906 Abstract Background Retrotransposons are an abundant component of eukaryotic genomes. The high quality of the Arabidopsis thaliana genome sequence makes it possible to comprehensively characterize retroelement populations and explore factors that contribute to their genomic distribution. Results We identified the full complement of A. thaliana long terminal repeat LTR retroelements using RetroMap a software tool that iteratively searches genome sequences for reverse transcriptases and then defines retroelement insertions. Relative ages of full-length elements were estimated by assessing sequence divergence between LTRs the Pseudoviridae were significantly younger than the Metaviridae. All retroelement insertions were mapped onto the genome sequence and their distribution was distinctly non-uniform. Although both Pseudoviridae and Metaviridae tend to cluster .
