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In order to identify men who are most suitable for prostate biopsy, there is a need to identify a group at high risk, not just of prostate cancer, but of significant prostate cancer. Several large studies have analyzed the clinical characteristics associated with the finding of higher grade (usually defined as Gleason score ≥7) prostate cancer on biopsy. Factors significantly associated with high grade cancer were: PSA level, smaller prostate volume, abnormal DRE findings, age, and black African and black Caribbean ethnicity, whereas a previous negative prostate biopsy reduced this risk. A false-positive PSA (or a PSA 4.0ng/mL) has consequences, firstly the collateral effects or complications of a prostate. | GASTROSTOMY Edited by Pavel Kohout INTECHWEB.ORG Gastrostomy Edited by Pavel Kohout Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Silvia Vlase Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat Image Copyright kentoh 2011. Used under license from Shutterstock.com First published November 2011 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Gastrostomy Edited by Pavel Kohout p. cm. ISBN 978-953-307-365-1 IkfTE IJ OPEN ACCESS INI Lvrl PUBLISHER INTECH open free online editions of InTech Books and Journals can be found at .
