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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Gene expression in primate liver during viral hemorrhagic fever | BioMed Central Virology Journal Research Gene expression in primate liver during viral hemorrhagic fever Mahmoud Djavani1 Oswald R Crasta2 Yan Zhang2 Juan Carlos Zapata1 Bruno Sobral2 Melissa G Lechner3 Joseph Bryant1 Harry Davis1 and Maria S Salvato 1 Address institute of Human Virology University of Maryland School of Medicine Baltimore MD 21201 USA Virginia Bioinformatics Institute at Virginia Tech Blacksburg VA 24061 USA and 3University of Southern California Keck School of Medicine Los Angeles CA 90089 USA Email Mahmoud Djavani - mdjavani@ihv.umaryland.edu Oswald R Crasta - ocrasta@vbi.vt.edu Yan Zhang - yzhang@vbi.vt.edu Juan Carlos Zapata - jzapata@ihv.umaryland.edu Bruno Sobral - bsobral@vbi.vt.edu Melissa G Lechner - lechner@usc.edu Joseph Bryant - jbryant@ihv.umaryland.edu Harry Davis - hdavis@ihv.umaryland.edu Maria S Salvato - msalvato@ihv.umaryland.edu Corresponding author Open Access Published 12 February 2009 Received 12 January 2009 Accepted 12 February 2009 Virology journal 2009 6 20 doi l0.ll86 l743-422X-6-20 This article is available from http www.virologyj.cOm content 6 1 20 2009 Djavani et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background Rhesus macaques infected with lymphocytic choriomeningitis virus LCMV provide a model for human Lassa fever. Disease begins with flu-like symptoms and progresses rapidly with fatal consequences. Previously we profiled the blood transcriptome of LCMV-infected monkeys M. Djavani et al J. Virol. 2007 showing distinct pre-viremic and viremic stages that discriminated virulent from benign infections. In the present study changes in liver gene expression from macaques .
