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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Hepatitis B virus genotypes and evolutionary profiles from blood donors from the northwest region of China | Virology Journal BioMed Central Open Access Hepatitis B virus genotypes and evolutionary profiles from blood donors from the northwest region of China Xing-bin Hu 1 Qiao-hong Yue2 Xian-qing Zhang1 Xue-qing Xu3 Yin Wen4 Yao-zhen Chen1 Xiao-dong Cheng2 Liu Yang2 and Shi-jie Mu 1 Address Department of Blood Transfusion Xijing Hospital the Fourth Military Medical University 17th Changlexi Road Xi an 710032 PR China 2Department of Clinic Molecular Research Center Clinic Diagnostic Laboratory Xijing Hospital Fourth Military Medical University 17th Changlexi Road Xi an 710032 PR China 3Department of Molecular Genetics Third Military Medical University Gaotanyan Chongqing 40038 PR China and 4Department of Electron Microscope Centralab Fourth Military Medical University 15th Changlexi Road Xi an 710032 PR China Email Xing-bin Hu - hxbyqh@fmmu.edu.cn Qiao-hongYue - hxbyqh@163.com Xian-qingZhang-Zhangxq@fmmu.edu.cn Xue-qing Xu - buyi_chu@gmail.com Yin Wen - yinwen@fmmu.edu.cn Yao-zhen Chen - chenyz@fmmu.edu.cn Xiao- dong Cheng - chengxd@fmmu.edu.cn Liu Yang - yangliu@fmmu.edu.cn Shi-jie Mu - musj1963@fmmu.edu.cn Corresponding authors Published 17 November 2009 Received 21 July 2009 Accepted 17 November 2009 Virology Journal 2009 6 199 doi 10.1186 1743-422X-6-199 This article is available from http www.virologyj.com content 6 1 199 2009 Hu et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Hepatitis B virus HBV is prevalent in China and screening of blood donors is mandatory. Up to now ELISA has been universally used by the China blood bank. However this strategy has sometimes failed due to the high frequency of nucleoside acid mutations. Understanding HBV evolution and strain diversity could help devise a better screening