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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Combined effects of hyperglycemic conditions and HIV-1 Nef: a potential model for induced HIV neuropathogenesis | Virology Journal BioMed Central Research Combined effects of hyperglycemic conditions and HIV-I Nef a potential model for induced HIV neuropathogenesis Edward A Acheampong1 Cassandra Roschel2 Muhammad Mukhtar3 Alagarsamy Srinivasan4 Mohammad Rafi5 Roger J Pomerantz6 and Zahida Parveen 1 Address The Dorrance H. Hamilton Laboratories Division of Infectious Diseases and Environmental Medicine PA 19107 USA 2Bioscience Technologies - Biotechnology Thomas Jefferson University Philadelphia PA 19107 USA 3Department of Biochemistry Pir Mehr Ali Shah Arid Agriculture University Rawalpindi 46300 Pakistan 4NanoBio Diagnostics West Chester PA 19382 USA 5Department of Neurology Jefferson Medical College Thomas Jefferson University Philadelphia PA 19107 USA and 6Tibotec Inc. 1020 Stony Hill Road Suite 300 Yardley PA 19067 USA Email Edward A Acheampong - eacheamp@yahoo.com Cassandra Roschel - Cassandra.Roschel@gmail.com Muhammad Mukhtar - mukhtar.muhammad@gmail.com Alagarsamy Srinivasan - alagarsamy.srinivasan@gmail.com Mohammad Rafi - Mohammad.Rafi@jefferson.edu Roger J Pomerantz - RPomeran@its.jnj.com Zahida Parveen - zahida.parveen@jefferson.edu Corresponding author Open Access Published 30 October 2009 Virology Journal 2009 6 183 doi 10.1186 I743-422X-6-I83 Received 4 May 2009 Accepted 30 October 2009 This article is available from http www.virologyj.cOm content 6 1 183 2009 Acheampong et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Hyperglycemic conditions associated with diabetes mellitus DM or with the use of antiretroviral therapy may increase the risk of central nervous system CNS disorders in HIV-1 infected patients. In support of this hypothesis we investigated the combined effects of hyperglycemic conditions and