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Báo cáo y học: " Comparative and functional genomics reveals genetic diversity and determinants of host specificity among reference strains and a large collection of Chinese isolates of the"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Comparative and functional genomics reveals genetic diversity and determinants of host specificity among reference strains and a large collection of Chinese isolates of the . | Open Access Comparative and functional genomics reveals genetic diversity and determinants of host specificity among reference strains and a large collection of Chinese isolates of the phytopathogen Xanthomonas campestris pv. campestris Yong-Qiang HeK Liang ZhangHt Bo-Le JiangH Zheng-Chun Zhang Rong-Qi Xu Dong-Jie Tang Jing Qin Wei Jiang Xia Zhang Jie Liao Jin-Ru Cao Sui-Sheng Zhang Mei-Liang Wei Xiao-Xia Liang Guang-Tao Lu Jia-Xun Feng Baoshan Chen Jing Cheng and Ji-Liang Tang Addresses Guangxi Key Laboratory of Subtropical Bioresources Conservation and Utilization and College of Life Science and Technology Guangxi University Daxue Road Nanning Guangxi 530004 People s Republic of China. tCapitalBio Corporation Life Science Parkway Changping District Beijing 102206 People s Republic of China. H These authors contributed equally to this work. Correspondence Ji-Liang Tang. Email jltang@gxu.edu.cn Received 10 June 2007 Revised 9 October 2007 Accepted l0 October 2007 Published 10 October 2007 Genome Biology 2007 8 R2l8 doi l0.ll86 gb-2007-8- l0-r2l8 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2007 8 l0 R2l8 2007 He et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. I t II I p II Abstract Background Xanthomonas campestris pathovar campestris Xcc is the causal agent of black rot disease of crucifers worldwide. The molecular genetic diversity and host specificity of Xcc are poorly understood. Results We constructed a microarray based on the complete genome sequence of Xcc strain 8004 and investigated the genetic diversity and host specificity of Xcc by array-based comparative genome hybridization analyses of l8 virulent strains. The results demonstrate that a .