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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A cornucopia of delights for the mouse fancier. | Meeting report A cornucopia of delights for the mouse fancier Dominic P Norris Sonja Nowotschin and Anna-Katerina Hadjantonakis Addresses MRC Mammalian Genetics Unit Harwell Oxfordshire OX11 0RD UK. Developmental Biology Program Sloan-Kettering Institute New York NY10021 USA. Published I November 2007 Genome Biology 2007 8 3I8 doi I0.II86 gb-2007-8-I0-3I8 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2007 8 I0 3I8 2007 BioMed Central Ltd A report on the Mouse Molecular Genetics meeting Hinxton UK 5-9 September 2007. This annual gathering of mouse enthusiasts covers many aspects of mouse molecular genetics epigenetics development and disease and also provides a forum for showcasing cutting-edge technologies and resources. This year s meeting was held at a new European location the Wellcome Trust campus in Hinxton outside Cambridge. A night at the movies The first night of the meeting was movie night. Microscopy is a mainstay of biology and it is becoming increasingly clear that in vivo imaging will be essential for revealing the dynamics underlying gene regulation lineage specification and embryonic morphogenesis. This point was beautifully highlighted in presentations from Sigolene Meilhac Institut Pasteur Paris France and Berenika Plusa Manchester University Manchester UK who tackled the problem of lineage specification epiblast versus primitive endoderm within the inner cell mass ICM of the blastocyst stage embryo. By imaging a nuclear-localized human histone H2B-green fluorescent protein GFP fusion protein in developing embryos Meilhac visualized the dynamics of all cells within the ICM. Using the same fluorescent fusion protein Plusa specifically followed the primitive endoderm cells as they become specified. The take-home message from these talks was that live imaging at cellular resolution will have a lot to reveal when applied beyond the analysis of preimplantation embryos to more complex .