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độ nhạy Disp: inj 3g/1g lọ SE: thiếu máu tán huyết, protein niệu sai + Ghi chú: Thông thường sử dụng trong kết hợp w / aminoglycosides, thâm nhập vào thần kinh trung ương với các kích thích màng não; Xem thêm ticarcillin Ticlopidine (Ticlid) Chú ý: bạch cầu trung tính / mất bạch cầu hạt, | 202 Ticlopidine sensitivity Disp Inj 3g 1g vial SE Hemolytic anemia false proteinuria Notes Often used in combo w aminoglycosides penetrates CNS with meningeal irritation see also ticarcillin Ticlopidine Ticlid WARNING Neutropenia agranulocytosis TTP aplastic anemia reported Uses ị risk of thrombotic stroke protect grafts status post CABG diabetic microangiopathy ischemic heart Dz DVT prophylaxis graft prophylaxis after renal transplant Action Plt aggregation inhibitor Dose 250 mg PO bid w food Caution B - T tox of ASA anticoagulation NSAIDs theophylline Contra Bleeding hepatic impair neutropenia thrombocytopenia Disp Tabs 250 mg SE Bleeding GI upset rash T on LFTs Notes Follow CBC 1st 3 mo Tigecycline Tygacil Uses Rx complicated skin soft tissue Infxns complicated intraabd Infxns Action New class related to tetracycline Spectrum Broad gram gram - anaerobic some mycobacterial E. coli Enterococcus faecalis vanco-susceptible isolates Staph aureus meth-susceptible resistant Strep agalactiae anginosus grp pyogenes Citrobacter freundii Enterobacter cloacae B. fragilis group C. perfringens Peptostreptococcus Dose Adults. 100 mg then 50 mg q12h IV over 30-60 min every 12 h Caution D hepatic impair monotherapy w intestinal perf not OK in peds Contra Component sensitivity Disp Inj 50 mg vial SE N V inj site Rxn Timolol Blocadren WARNING Exacerbation of ischemic heart Dz w abrupt D C Uses HTN MI Action p-adrenergic receptor blocker p1 p2 Dose HTN 10-20 mg bid up to 60 mg d. MI 10 mg bid Caution C 1st tri D if 2nd or 3rd tri Contra CHF cardiogenic shock bradycardia heart block COPD asthma Disp Tabs 5 10 20 mg SE Sexual dysfunction arrhythmia dizziness fatigue CHF Timolol Ophthalmic Timoptic Uses Glaucoma Action p-blocker Dose 0.25 1 gt bid ị to daily when controlled use 0.5 if needed 1 gtt d gel Caution C 1st tri D 2nd or 3rd Disp Soln 0.25 0.5 Timoptic XE 0.25 0.5 gel-forming soln SE Local irritation Tinidazole Tindamax WARNING Off-label use discouraged animal .
