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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Sequence diversity in three tomato species: SNPs, markers, and molecular evolution | BMC Plant Biology BioMed Central Open Access Research article Sequence diversity in three tomato species SNPs markers and molecular evolution José M Jiménez-Gómez and Julin N Maloof Address Department of Plant Biology College of Biological Sciences University of California Davis Davis CA 95616 USA Email José M Jiménez-Gómez - jmjimenez@ucdavis.edu Julin N Maloof - jnmaloof@ucdavis.edu Corresponding author Published 3 July 2009 Received 16 September 2008 BMC Plant Biology 2009 9 85 doi 10.1186 1471-2229-9-85 Accepted 3 July 2009 This article is available from http www.biomedcentral.com 1471-2229 9 85 2009 Jiménez-Gómez and Maloof licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Tomato species are of significant agricultural and ecological interest with cultivated tomato being among the most common vegetable crops grown. Wild tomato species are native to diverse habitats in South America and show great morphological and ecological diversity that has proven useful in breeding programs. However relatively little is known about nucleotide diversity between tomato species. Until recently limited sequence information was available for tomato preventing genome-wide evolutionary analyses. Now an extensive collection of tomato expressed sequence tags ESTs is available at the SOL Genomics Network SGN . This database holds sequences from several species annotated with quality values assembled into unigenes and tested for homology against other genomes. Despite the importance of polymorphism detection for breeding and natural variation studies such analyses in tomato have mostly been restricted to cultivated accessions. Importantly previous polymorphisms surveys mostly ignored the linked meta-information limiting .