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Health Implications of Perchlorate Ingestion

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In 1985, perchlorate contamination was discovered at Superfund sites in California; however, the extent of perchlorate contamination of water sources nationwide was not revealed until 1997. Today, over 11 million people have perchlorate in their public drinking-water supplies at concentrations of 4 ppb (4 :g/L) or higher. Because of the controversy surrounding the concentration at which perchlorate should be regulated, the Department of Defense (DOD), the Department of Energy (DOE), the National Aeronautics and Space Administration (NASA), and the Environmental Protection Agency (EPA) asked the National Research Council to assess the potential adverse health effects of perchlorate ingestion from clinical, toxicologic, medical, and public-health perspectives | health Implications of Perchlorate Ingestion NATIONAL RESEARCH COUNCIL OF THE NATIONAL ACADEMIES --ư . -f fd -Pealth Implications of Perchlorate Ingestion Committee to Assess the Health Implications of Perchlorate Ingestion Board on Environmental Studies and Toxicology Division on Earth and Life Studies NATIONAL RESEARCH COUNCIL OF THE NATIONAL ACADEMIES TLJC K ATI - iN A A A r EA A ICC ĐĐCCC I nt NAiiOinAl ACAƯtnAltồ rKtoo Washington D.c. www.nap.edu THE NATIONAL ACADEMIES PRESS 500 Fifth Street NW Washington DC 20001 NOTICE The project that is the subject of this report was approved by the Governing Board of the National Research Council whose members are drawn from the councils of the National Academy of Sciences the National Academy of Engineering and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance. This project was supported by Contract 68-C-03-081 between the National Academy of Sciences and the U.S. Environmental Protection Agency U.S. Department of Defense U.S. Department of Energy and National Aeronautics and Space Administration. Any opinions findings conclusions or recommendations expressed in this publication are those of the author s and do not necessarily reflect the view of the organizations or agencies that provided support for this project. International Standard Book Number 0-309-09568-9 Book International Standard Book Number 0-309-54811-X PDF Library of Congress Control Number 2005925051 Additional copies of this report are available from The National Academies Press 500 Fifth Street NW Box 285 Washington DC 20055 800-624-6242 202-334-3313 in the Washington metropolitan area http www.nap.edu Copyright 2005 by the National Academy of Sciences. All rights reserved. Printed in the United States of .

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