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In order to obtain the sample, the universe of municipalities was those with little more than 100.000 individuals. The municipalities were classified in 25 strata according to geographical region, population size living in the urban part of the municipality, the value of synthetic index for quality of life (QLI) as well as education and health infrastructure. 6 Two treatment municipalities were randomly selected within each stratum among the municipalities participating in Familias en Accion. For each treatment municipality, a control municipality was chosen as the most similar to the treatment municipality in terms of population size, population living in the urban. | New ESPGHAN guidelines for the diagnosis of Coeliac Disease in Children and Adolescents Steffen Husby Hans Christian Andersen Children s Hospital Odense University Hospital Denmark Agenda Change in clinical paradigm Definitions of coeliac disease New diagnostic guidelines Algorithms Interlaken ESPGHAN criteria 1979 1. Small intestinal biopsy villous atrophy 2. Gluten free diet for 1-2 years 3. Biopsy normal. 4. Re-introduction of gluten 5. Biopsy villous atrophy McNeish et al. Arch Dis Childh 1979 54 .
