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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Neuropathy caused by B12 deficiency in a patient with ileal tuberculosis: A case report | Journal of Medical Case Reports BioMed Central Case report Open Access Neuropathy caused by BI2 deficiency in a patient with ileal tuberculosis A case report Taraneh Dormohammadi Toosi Farhad Shahi Ali Afshari Nader Roushan and Marjan Kermanshahi Address Imam Khomeini Hospital Tehran University of Medical Sciences Keshavarz Blvd. Tehran Iran Email Taraneh Dormohammadi Toosi - dormohammadi@tums.ac.ir Farhad Shahi - fshahi@yahoo.com Ali Afshari - ali_afshari@tums.ac.ir Nader Roushan - nroshan@tums.ac.ir Marjan Kermanshahi - muji8@aol.com Corresponding author Published 21 March 2008 Received 14 July 2007 Journal of Medical Case Reports 2008 2 90 doi 10.1186 1752-1947-2-90 Accepted 21 March 2008 This article is available from http www.jmedicalcasereports.cOm content 2 1 90 2008 Toosi et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Vitamin B12 deficiency can result in macrocytic anemia. Neurologic abnormalities of B12 deficiency include sensory deficits loss of deep tendon reflexes movement disorders neuropsychiatric changes and seizures. Segmental involvement of the distal ileum such as in tuberculosis can cause vitamin B12 deficiency. To our knowledge macrocytic anemia with unusual manifestations such as brain atrophy and seizures due to intestinal tuberculosis has not been reported in the literature. Case presentation A 14-year-old girl presented with complaints of paraplegia ataxia fever and fatigue that had started a few months earlier and which had been getting worse in the last three weeks. Her laboratory results were indicative of macrocytic anemia with a serum B12 level 100 normal 160-970 pg ml and hypersegmented neutrophils. Her MRI findings showed brain atrophy. Her fever workup eventually
