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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Anemia and blood transfusion in a surgical intensive care unit. | Sakr et al. Critical Care 2010 14 R92 http ccforum.eom content 14 3 R92 c CRITICAL CARE RESEARCH Open Access Anlemia and blood transfusion in a surgical intensive care unit Yasser Sakr 1 Suzana Lobo1 Stefanie Knuepfer1 Elizabeth Esser1 Michael Bauer1 Utz Settmacher2 Dagmar Barz3 and Konrad Reinhart1 Abstract Introduction Studies in intensive care unit ICU patients have suggested that anemia and blood transfusions can influence outcomes but these effects have not been widely investigated specifically in surgical ICU patients. Methods We retrospectively analyzed the prospectively collected data from all adult patients 18 years old admitted to a 50-bed surgical ICU between 1st March 2004 and 30th July 2006. Results Of the 5925 patients admitted during the study period 1833 30.9 received a blood transfusion in the ICU. Hemoglobin concentrations were 9 g dl on at least one occasion in 57.6 of patients. Lower hemoglobin concentrations were associated with a higher Simplified Acute Physiology Score II and Sequential Organ Failure Assessment score greater mortality rates and longer ICU and hospital lengths of stay. Transfused patients had higher ICU 12.5 vs. 3.2 and hospital 18.3 vs. 6.5 mortality rates both p 0.001 than non-transfused patients. However ICU and in-hospital mortality rates were similar among transfused and non-transfused matched pairs according to a propensity score n 1184 pairs and after adjustment for possible confounders in a multivariable analysis higher hemoglobin concentrations RR 0.97 0.95-0.98 per 1 g dl p 0.001 and blood transfusions RR 0.96 0.92-0.99 p 0.031 were independently associated with a lower risk of in-hospital death especially in patients aged from 66 to 80 years in patients admitted to the ICU after non-cardiovascular surgery in patients with higher severity scores and in patients with severe sepsis. Conclusions In this group of surgical ICU patients anemia was common and was associated with higher morbidity and mortality. Higher .
