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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Hypersensitivity to intravenous ondansetron: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Hypersensitivity to intravenous ondansetron a case report Karishma K Mehra1 Nithya J Gogtay 1 Rohan Ainchwar2 and Lata S Bichile2 Address Department of Clinical Pharmacology Seth GS Medical College KEM Hospital Parel Mumbai 400012 India and 2Department of Medicine Seth GS Medical College KEM Hospital Parel Mumbai 400012 India Email Karishma K Mehra - karishma84@gmail.com Nithya J Gogtay - njgogtay@hotmail.com Rohan Ainchwar - not@valid.com Lata S Bichile - lsbichile@rediffmail.com Corresponding author Published 14 August 2008 Received 21 January 2008 Journal of Medical Case Reports 2008 2 274 doi l0.ll86 l752-l947-2-274 Accepted 14 August 2008 This article is available from http www.jmedicalcasereports.cOm content 2 l 274 2008 Karishma et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Ondansetron a 5-hydroxytryptamine3 receptor antagonist widely used in the prevention and treatment of chemotherapy-induced nausea and vomiting is associated with various unusual adverse drug reactions. In this paper we describe a hypersensitivity reaction to a single intravenous dose of ondansetron. Case presentation A l9-year-old woman presented to the emergency department of our institute with 3-4 episodes of nausea vomiting and epigastric distress. She had a diagnosis of polycystic ovarian disease and had been on treatment with cyproterone acetate 2 mg ethinyl estradiol 0.035 mg finasteride 5 mg and metformin 500 mg for a month. She had been taking oral roxithromycin 500 mg per day for the past 3 days for treatment of a mild upper respiratory tract infection. She also occasionally took rabeprazole l0 mg for gastritis which had worsened after .
