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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Prevalence, correlates and pattern of hepatitis B surface antigen in a low resource setting | Eke et al. Virology Journal 2011 8 12 http www.virologyj.eom content 8 1 12 J VIROLOGY JOURNAL RESEARCH Open Access Prevalence correlates and pattern of hepatitis B surface antigen in a low resource setting Ahizechukwu C Eke1 Uzoamaka A Eke2 Charles I Okafor3 Ifeanyichukwu U Ezebialu3 Chukwuanugo Ogbuagu4 Abstract Background Hepatitis B virus HBV infection in Nigeria has remained a Public Health issue. It is a major cause of mortality especially in developing countries. Vertical transmission of hepatitis B virus infection is thought to be a major route of transmission in low resource areas. In spite of this routine antenatal screening for hepatitis B infection is not yet practiced in many Nigerian hospitals. This paper present the findings of a study conducted among antenatal women in Nnewi Nigeria. Methods It was a cross-sectional study carried out over a 3-month period August - October 2009 . Recruitment of 480 women attending antenatal clinics in Nnewi Nigeria was done by simple random sampling using computer generated random numbers. HBsAg screening was done using rapid ELISA Kits. Statistical analysis was computed using STATA 11 package. The results were subjected to analysis using cross tabulations to explore statistical relationships between variables. Chi square test was used to explore proportional relationship between groups. The level of statistical significance was set at p 0.05 providing 95 confidence interval . Results Four hundred and eighty pregnant women were recruited into the study. Of these 40 tested positive to HBsAg accounting for 8.3 of the sample population. The age of the subjects studied varied from 14 to 45 years mean age - 24.3 years while the mean parity was 2.18. The HIV HBV co-infection rate was 4.2 . The vertical transmission rate was 51.6 . There were statistically significant relationships between HBV infection and previous history of tribal marks tattoos c2 27.39 P 0.001 df 1 history of contact with previously infected HBV .
