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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Correlation between parameters at initiation of renal replacement therapy and outcome in patients with acute kidney injury. | Available online http ccforum.eom content 13 6 R175 Research Correlation between parameters at initiation of renal replacement therapy and outcome in patients with acute kidney injury Marlies Ostermann1 and René WS Chang2 Open Access Department of Critical Care Guy s St Thomas Foundation Hospital Westminster Bridge Road SE1 7EH UK department of Nephrology Transplantation St George s Hospital Blackshaw Road SW17 0QT UK Corresponding author Marlies Ostermann Marlies@ostermann.freeserve.co.uk Received 17 Aug 2009 Revisions requested 7 Oct 2009 Revisions received 26 Oct 2009 Accepted 4 Nov 2009 Published 4 Nov 2009 Critical Care 2009 13 R175 doi 10.1186 cc8154 This article is online at http ccforum.com content 13 6 R1 75 2009 Ostermann and Chang et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Renal replacement therapy RRT is a fully established treatment for critically ill patients with acute kidney injury AKI but there are no scientifically established criteria when to initiate it. Our objectives were to describe the epidemiology of critically ill patients with AKI receiving RRT and to evaluate the relationship between biochemical physiological and comorbid factors at time of RRT and ICU mortality. Methods Retrospective analysis of demographic and physiologic data of 1 847 patients who received RRT for AKI in 22 ICUs in UK and Germany between 1989 - 1999. Results 54.1 of RRT patients died in ICU. ICU survivors were younger had a lower APACHE II score and fewer failed organ systems on admission to ICU compared to non-survivors. Multivariate analysis showed that at time of initiation of RRT independent risk factors for ICU mortality were mechanical ventilation odds ratio OR 6.03 neurological failure
