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The inevitability of a disease sounds a clarion for its prevention, or at least its control. Understanding its pathophysiology is essential to that process. For osteoarthritis, preconceived notions and mythology must be transcended to allow identification of its essentials. The first step was to establish a scientific basis for its recognition. Sorting associated phenomenon allowed identification of those which are non-diagnostic, and one major finding which is pathognomonic: the joint osteophyte. Once that was distinguished from the asymptomatic vertebral body, osteophytes identifying spondylosis deformans, a major impediment to disease understanding, was eliminated. While animal models have been sought or manufactured to address the question, this new understanding afforded a. | PRINCIPLES OF OSTEOARTHRITIS - ITS DEFINITION CHARACTER DERIVATION AnD MODALITY-RELATED RECOGNITION Edited by Bruce M. Rothschild INTECHWEB.ORG Principles of Osteoarthritis - Its Definition Character Derivation and Modality-Related Recognition Edited by Bruce M. Rothschild Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Vana Persen Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published February 2012 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Principles of Osteoarthritis - Its .
