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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Hypervascular nodule in a fibrotic liver overloaded with iron: identification of a premalignant area with preserved liver architecture. | Comparative Hepatology BioMed Central Case Report Open Access Hypervascular nodule in a fibrotic liver overloaded with iron identification of a premalignant area with preserved liver architecture António Sá Cunha Jean-Frédéric Blanc Hervé Trillaud Victor De Ledinghen Charles Balabaud and Paulette Bioulac-Sage Address Fédération d hépato-gastroentérologie CHU Bordeaux GREF Inserm E362 Université Bordeaux 2 France Email António Sá Cunha - antonio.sa-cunha@chu-bordeaux.fr Jean-Frédéric Blanc - jean-frederic.blanc@chu-bordeaux.fr Hervé Trillaud - herve.trillaud@chu-bordeaux.fr Victor De Ledinghen - victor.deledinghen@chu-bordeaux.fr Charles Balabaud - charles.balabaud@chu-bordeaux.fr Paulette Bioulac-Sage - paulette.bioulac-sage@chu-bordeaux.fr Corresponding author Published 04 May 2005 Received 21 December 2004 Comparative Hepatology 2005 4 5 doi l0.ll86 l476-5926-4-5 Accepted 04 May 2005 This article is available from http www.comparative-hepatology.cOm content 4 1 5 2005 Sá Cunha et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The presence of a hypervascular nodule in a patient with cirrhosis is highly suggestive of a hepatocellular carcinoma. Case presentation A 55 year old man with idiopathic refractory anaemia was addressed for the cure of a recently appeared 3.3 cm hypervascular liver nodule. The nodule was not visible on the resected fresh specimen but a paler zone was seen after formalin fixation. The surrounding liver was fibrotic METAVIR score F3 and overloaded with iron. However the paler zone thought to be the nodule had in fact a normal architecture was less fibrotic and contained some portal tractlike structures but with arteries only moreover this paler area was devoid of iron contained