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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Tenecteplase for ST-elevation myocardial infarction in a patient treated with drotrecogin alfa (activated) for severe sepsis: a case report. | Journal of Medical Case Reports BioMed Central Open Access Case report Tenecteplase for ST-elevation myocardial infarction in a patient treated with drotrecogin alfa activated for severe sepsis a case report Lillian Barra1 Jeffrey Shum1 J Geoffrey Pickering2 and Raymond Kao 1 Address division of Critical Care Department of Medicine University of Western Ontario Commissioner s Rd London Ontario Canada and 2Division of Cardiology Department of Medicine University of Western Ontario Commissioner s Rd London Ontario Canada Email Lillian Barra - lbarra@uwo.ca Jeffrey Shum - Jeffrey.Shum@londonhospitals.ca J Geoffrey Pickering - gpickering@robarts.ca Raymond Kao - rkao3@uwo.ca Corresponding author Published 5 November 2009 Received 7 August 2008 Journal of Medical Case Reports 2009 3 109 doi 10.1186 1752-1947-3-109 Accepted 5 November 2009 This article is available from http www.jmedicalcasereports.com content 3 1 109 2009 Barra et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Drotrecogin alfa activated DrotAA an activated protein C promotes fibrinolysis in patients with severe sepsis. There are no reported cases or studies that address the diagnosis and treatment of myocardial infarction in septic patients treated with DrotAA. Case presentation A 59-year-old Caucasian man with septic shock secondary to community-acquired pneumonia treated with DrotAA subsequently developed an ST-elevation myocardial infarction 12 hours after starting DrotAA. DrotAA was stopped and the patient was given tenecteplase thrombolysis resulting in complete resolution of ST-elevation and no adverse bleeding events. DrotAA was restarted to complete the 96-hour course. The sepsis resolved and the patient was discharged from .
