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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Russell bodies in a skin biopsy: a case report | Journal of Medical Case Reports BioMed Central Case report Russell bodies in a skin biopsy a case report Joanne Verheij Elisabeth H Jaspars Paul van der Valk and Lawrence Rozendaal Open Access Address Department of Pathology VU University Medical Center De Boelelaan 1117 1081 HV Amsterdam The Netherlands Email Joanne Verheij - joanne.verheij@erasmusmc.nl Elisabeth H Jaspars - eh.jaspars@vumc.nl Paul van der Valk - p.vandervalk@vumc.nl Lawrence Rozendaal - l.rozendaal@vumc.nl Corresponding author Published 4 November 2009 Received 27 May 2008 Journal of Medical Case Reports 2009 3 108 doi 10.1186 1752-1947-3-108 Accepted 4 November 2009 This article is available from http www.jmedicalcasereports.com content 3 1 108 2009 Verheij et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction The presence of eosinophilic bodies in a skin biopsy can be found in a variety of situations and this may present a challenge to the pathologist. The differential diagnosis of these eosinophilic structures include microorganisms such as histoplasmosis or cryptococcosis fungi Michaelis-Gutmann bodies deposits of amyloid or immunoglobulins colloid bodies or elastic bodies. Case presentation During a routine examination of a skin biopsy with actinic keratosis taken from the cheek of a 61-year-old man clusters of eosinophilic bodies were seen within an inflammatory infiltrate in the dermis both intracytoplasmic and extracellular. Using additional immunohistochemical staining these structures were identified as polyclonal Russell bodies. Conclusion The differential diagnosis of intracytoplasmic eosinophilic structures in a skin biopsy includes Russell bodies an uncommon finding that may be associated with chronic inflammatory .
