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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Liposarcoma of the forearm in a man with type 1 neurofibromatosis: a case report | JOURNAL OF MEDICAL Sr CASE REPORTS Case report Liposarcoma of the forearm in a man with type 1 neurofibromatosis a case report Markus Dietmar Schofer Mohammed Yousef Abu-Safieh Jurgen Paletta Susanne Fuchs-Winkelmann and Bilal Farouk El-Zayat Open Access Address Department of Orthopaedics University Hospital Marburg Baldingerstrasse 35033 Marburg Germany Email MDS - schofer@med.uni-marburg.de MYAS - abusafie@med.uni-marburg.de JP - paletta@med.uni-marburg.de SFW - fuchss@med.uni-marburg.de BFEZ - elzayat@med.uni-marburg.de Corresponding author Published 29 April 2009 Received 16 June 2008 Journal of Medical Case Reports 2009 3 7071 doi 10.1186 1752-1947-3-7071 Accepted 5 April 2009 This article is available from http jmedicalcasereports.Com jmedicalcasereports article view 3 4 7071 2009 Schofer et al licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 3.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction The combination of neurofibromatosis and liposarcoma is very rare. We present a case of a dedifferentiated liposarcoma in the forearm as a complication in a patient with neurofibromatosis type 1. Case presentation A Caucasian man with neurofibromatosis type 1 presented at our clinic complaining of a slow growing swelling on his left forearm over a period of one and a half years. Clinical examination and history pointed to malignancy. Radiological examination inclusive of magnetic resonance imaging and positron emission tomography confirmed our suspicion. A final diagnosis of dedifferentiated high-grade liposarcoma with axillary lymph node metastases was established after a pathological examination of a tumour biopsy. The consulting tumour board recommended either an elbow exarticulation or an accurate radical local resection including the metastatic axillary .