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Dermatologic Diseases See Tables 32-1, 32-2, and 32-3 and Chaps. 52, 53, 54, 55, and 56. Table 32-3 White Lesions of Oral Mucosa Condition Usual Location Clinical Features Course Lichen planus Buccal Striae, white Protracted; mucosa, tongue, plaques, red areas, ulcers responds to topical gingiva, lips; skin and in mouth; purplish glucocorticoids papules on skin; may be asymptomatic, sore, or painful; lichenoid drug reactions similar may look White sponge nevus Oral Painless white Benign and mucosa, vagina, thickening of epithelium; permanent anal mucosa adolescent/early onset; familial adult Smoker's leukoplakia Any area White patch that May or may and of oral mucosa, may become firm, rough, not resolve with or red-fissured and cessation of habit | Chapter 032. Oral Manifestations of Disease Part 5 Dermatologic Diseases See Tables 32-1 32-2 and 32-3 and Chaps. 52 53 54 55 and 56. Table 32-3 White Lesions of Oral Mucosa Condition Usual Location Clinical Features Course Lichen planus Buccal mucosa tongue Striae white plaques red areas ulcers Protracted responds to topical gingiva and lips skin in mouth purplish papules on skin may be asymptomatic sore or painful lichenoid drug reactions may look similar glucocorticoids White sponge nevus Oral mucosa vagina anal mucosa Painless white thickening of epithelium adolescent early adult onset familial Benign and permanent Smoker s leukoplakia and smokeless tobacco lesions Any area of oral mucosa sometimes related to location of habit White patch that may become firm rough or red-fissured and ulcerated may become sore and painful but usually painless May or may not resolve with cessation of habit 2 develop squamous cell carcinoma early biopsy essential Erythroplaki Floor of Velvety reddish High risk of a with or without white patches mouth common in men tongue and buccal mucosa in women plaque occasionally mixed with white patches or smooth red areas squamous cell cancer early biopsy essential Candidiasis Any area in mouth Pseudomembrano us type thrush creamy white curdlike patches that reveal a raw bleeding surface when scraped found in sick infants debilitated elderly patients receiving high doses of glucocorticoids or broadspectrum antibiotics or in patients with AIDS Responds favorably to antifungal therapy and correction of predisposing causes where possible Erythematous type flat red sometimes Course same as .