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Bài viết Một công thức mới có tác dụng xua muỗi đẻ trứng vào ổ nước và ức chế trứng nở góp phần kiểm soát vector truyền bệnh sốt xuất huyết trình bày phương pháp chế tạo công thức MCA; Phương pháp đánh giá hiệu quả của công thức MCA; Phương pháp tạo muối natri anacardat; Hiệu quả kiểm soát muỗi Aedes của công thức MCA. | Vietnam Journal of Community Medicine Vol 63 No 3 2022 15-20 INSTITUTE OF COMMUNITY HEALTH A NEW FORMULATION INHIBITS EGG HATCHING AND REPELS MOSQUITO OVIPOSITION AT BREEDING SITES CONTRIBUTING TO THE CONTROL OF DENGUE VECTOR Phung Thi Kim Hue1 4 Le Tri Vien1 Dau Minh Nga4 Nguyen Thi Thanh Nga4 Than Trong Quang3 Tran Van Loc1 2 1 Institute of Health Research and Educational Development in Central Highlands - 73 Le Hong Phong Dien Hong Pleiku city Gia Lai Vietnam 2 Institute of Chemistry Vietnam Academy of Science and Technology - 8 Hoang Quoc Viet Nghia Do Cau Giay Hanoi Vietnam 3 Tay Nguyen University - 567 Le Duan Ea Tam Buon Ma Thuot city Dak Lak Vietnam 4 Hung Vuong Gifted High School - 48 Hung Vuong Dien Hong Pleiku city Gia Lai Vietnam Received 17 12 2021 Revised 25 01 2022 Accepted 04 03 2022 ABSTRACT Anacardium occidentale is a typical plant species in tropical countries including Vietnam. Its nut shell extracts possess biological effects such as larviciding. Solvent extracts of the nut shell of this plant were reported to contain 62.9 anacardic acid AA . However AA is a liquid mixture of four compounds differentiating by the hydrophobicity of side chains making it water-insoluble. In this study we aim to overcome this drawback by converting AA into a sodium salt which exists in anionic condition and then combine with ethanol extract of lime peel to create a new pellet product MCA to evaluate the ovicidal and repellent activities against Aedes mosquitoes at their breeding grounds. The results showed that the efficiency of yielding salt form from the AA liquid extract was 96 which was then mixed with lime peel extract and additives at a 2 1 7 ratio to produce MCA pellets. The formulation demonstrated egg hatch inhibition upon Ae. aegypti 82.9 and Ae. albopictus 90.6 at 50 ppm compared to the negative control P0.05 . Similarly at the same concentration MCA exhibited 68.5 and 78.1 repellent activities toward Ae. albopictus and Ae. aegypti from the breeding .