tailieuchung - DISC: A highly scalable and accurate inference of gene expression and structure for single-cell transcriptomes using semisupervised deep learning

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DISC: A highly scalable and accurate inference of gene expression and structure for single-cell transcriptomes using semisupervised deep learning

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Dropouts distort gene expression and misclassify cell types in single-cell transcriptome. Although imputation may improve gene expression and downstream analysis to some degree, it also inevitably introduces false signals. We develop DISC, a novel deep learning network with semi-supervised learning to infer gene structure and expression obscured by dropouts. |

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DISC: A highly scalable and accurate inference of gene expression and structure for single-cell transcriptomes using semisupervised deep learning

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