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Bài viết trình bày mô tả đặc điểm hình ảnh của nhồi máu não cấp trên cộng hưởng từ thường quy và chụp mạch máu bằng kỹ thuật TOF 3D và khảo sát sự thay đổi giá trị khuếch tán biểu kiến theo thời gian nhồi máu. | NGHIÊN CỨU KHOA HỌC KHẢO SÁT ĐẶC ĐIỂM CỦA NHỒI MÁU NÃO CẤP TRÊN CỘNG HƯỞNG TỪ SCIENTIFIC RESEARCH THƯỜNG QUI VÀ CHỤP MẠCH MÁU BẰNG KỸ THUẬT TOF 3D Nguyễn Viết Lợi Võ Thị Thúy Hằng Lê Quang Khang Nguyễn Thị Phương Loan Phan Công Chiến Phạm Ngọc Hoa SUMMARY Objective. To describe the characteristics of acute ischemic stroke on conventional magnetic resonance imaging MRI and angiography using TOF 3D technique and to evaluate the time course of the apparent diffusion coefficient after cerebral infarction. Materials and Methods. We conducted a retrospective study in 221 patients with acute ischemic stroke who were performed MRI at the University Medical Center Hospital between January 2018 and December 2020. A radiologist who had more than 5 years of experience of MRI evaluates the changes of signal intensity on these sequences T1- weighted T2-weighted FLAIR DWI ADC Susceptibility weighted imaging SWI and TOF3D. Results The study was composed of 221 patients 136 males 85 females . The mean age of patients was 64.5 13.7 years range 28- 96 years . 60 - 79 age group accounts for the majority with 105 people 47.5 . Anterior cerebral artery territory infarcts and cerebral peduncular infarction were the least common 1.1 . The rate of brain parenchymal signal abnormalities on the T1W T2W FLAIR DWI ADC sequences respectively was 85.5 87.3 90.0 and 97.3 . The rate of a significant decrease in vascular signaling on TOF3D was 35.7 . The rate of susceptibility vessel sign and prominent vessel sign on SWI was 21.8 và 9.1 respectively. Immediately following a cerebral infarction the relative ADC rADC value begins to decrease gradually and reaches its lowest level between day 2 and 4. Thereafter the rADC value increases gradually and reaches a pseudonormalization around day 7. Conclusion Magnetic resonance imaging is of high value in the diagnosis of acute ischemic stroke. Diffusion imaging has the highest sensitivity in lesion detection. TOF3S and SWI were helpful in depiction the .