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Biofilm is an aggregate of microorganisms forming multicellular communities where cells are stuck cooperatively by a produced by oneself Matrix Extracellularis. Biofilm formation by microorganisms is a ubiquitous, omnipresent & active mechanism. This vigorous ability of microbes to form biofilms proves to be a key technique for resisting and surviving in adverse climatic conditions as well as antibacterial compounds. Numerous features of biofilms contributed by component of extracellular matrix and microbial community allows in tolerating adverse conditions. Microbes in a biofilm have a remarkable property of resistance against antimicrobials, in contrast with free-swimming planktonic cells. |