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Assessment and refinement of eukaryotic gene structure prediction with gene-structure-aware multiple protein sequence alignment

Anh Khoa 59 13 pdf

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Accurate computational identification of eukaryotic gene organization is a long-standing problem. Despite the fundamental importance of precise annotation of genes encoded in newly sequenced genomes, the accuracy of predicted gene structures has not been critically evaluated, mostly due to the scarcity of proper assessment methods. |

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