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Cholesterol-lowering and hepatoprotective effect of fruit juice extract of Azadirachta indica on Plasmodium berghei infected mice

The effect of fresh juice extract of Azadirachta indica on lipid profile and hepatic function of Plasmodium berghei infected albino mice were investigated. Thirty adult male mice were placed in five groups of six mice each, acclimatized for 7 days and used for the study. Group A was normal control and had free access to feed and water while groups B to E were infected with Plasmodium berghei, and confirmed of parasitamia on the third day. Groups C, D and E were further given standard anti malaria drug (5 mg/kg body weight of Artesunate), 4.3ml/kg and 8.6 ml/kg of fruit juice extract respectively for fourteen days and sacrificed. |