Đang chuẩn bị liên kết để tải về tài liệu:
Tracking intratumoral heterogeneity in glioblastoma via regularized classification of single-cell RNA-Seq data

Understanding cellular and molecular heterogeneity in glioblastoma (GBM), the most common and aggressive primary brain malignancy, is a crucial step towards the development of effective therapies. Besides the inter-patient variability, the presence of multiple cell populations within tumors calls for the need to develop modeling strategies able to extract the molecular signatures driving tumor evolution and treatment failure. |