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Nrf2 is required to maintain the self-renewal of glioma stem cells

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Glioblastomas are deadly cancers that display a functional cellular hierarchy maintained by selfrenewing glioma stem cells (GSCs). Self-renewal is a complex biological process necessary for maintaining the glioma stem cells. Nuclear factor rythroid 2-related factor 2(Nrf2) plays a significant role in protecting cells from endogenous and exogenous stresses. |

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