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A GSDMB enhancer-driven HSV thymidine kinaseexpressing vector for controlling occult peritoneal dissemination of gastric cancer cells

Gastric cancer (GC) is one of the major malignant diseases worldwide, especially in Asia, and Japan and Korea have the highest incidence in the world. Because most of the cases that are refractory to therapies die due to peritoneal dissemination (PD) of the cancer cells, controlling PD is important for patient survival. GSDMB is a member of the gasdermin gene family. |