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Gene expression and repression in insects is regulated through epigenetic mechanisms i.e. DNA Methylation, Histone modification and Noncoding RNAs which influence the phenotypic modification. In recent days insects are used as models in studying epigenetics. RNA interference (RNAi), also known as RNA silencing, refers to a set of molecular processes in which noncoding RNA molecules target and silence the expression of specific nucleic acids. Silencing Dnmt3 expression in newly hatched honeybee larvae mimics the effect of royal jelly, namely, the larvae destined to become workers develop into queens with fully developed ovaries. The detailed mechanisms of epigenetics in insect were discussed in the paper. |
