Đang chuẩn bị liên kết để tải về tài liệu:
MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancer

Cancer cells exhibit an altered metabolism, which is characterized by a preference for aerobic glycolysis more than mitochondrial oxidation of pyruvate. Mitochondrial pyruvate carrier 1 (MPC1) and mitochondrial pyruvate carrier 2 (MPC2) play a bottleneck role by transporting pyruvate into mitochondrial through the mitochondrial inner membrane. |