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Suppression of Mig-6 overcomes the acquired EGFR-TKI resistance of lung adenocarcinoma

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The resistance of lung cancer to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is one of the unconquered frontiers in chemotherapy. Mitogen-inducible gene 6 (Mig-6) is known to inhibit the kinase activity of epidermal growth factor receptor (EGFR). | Suppression of Mig-6 overcomes the acquired EGFR-TKI resistance of lung adenocarcinoma

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