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Prophylactic intervention of probiotics (L.acidophilus, L.rhamnosus GG) and celecoxib modulate Bax-mediated apoptosis in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis

Colorectal cancer has been found to be attenuated either with prophylactic manipulation of gut microbiome with probiotics or celecoxib, a non-steroidal anti-inflammatory drug mainly by suppressing early procarcinogenic markers in various experimental studies. | Prophylactic intervention of probiotics L.acidophilus L.rhamnosus GG and celecoxib modulate Bax-mediated apoptosis in 1 2-dimethylhydrazine-induced experimental colon carcinogenesis